Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630134 | 0.81 | CA12 (0.38) | DPP4CA12CA9KDM4EGLA | |
| SCHEMBL28888143 | 0.73 | CA12 (0.46) | CA12CA9KDM4EGLAHPGD | |
| SCHEMBL17227896 | 0.72 | CYP19A1 (0.36) | KDM4EMEN1GAAKMT2A | |
| SCHEMBL17220879 | 0.72 | CYP19A1 (0.36) | KDM4EMEN1GAAKMT2A | |
| SCHEMBL28424988 | 0.69 | CA12 (0.45) | CA12CA9KDM4EGLAHPGD | |
| SCHEMBL7731885 | 0.68 | PRKDC (0.34) | CA12CA9KDM4EHPGDALDH1A1 | |
| SCHEMBL643216 | 0.67 | KDM1A (0.38) | KDM4EHPGDALDH1A1LMNAMAPT | |
| SCHEMBL18049790 | 0.66 | HPRT1 (0.32) | CA12CA9HPRT1 | |
| SCHEMBL9245394 | 0.63 | ALDH1A1 (0.41) | CA12CA9KDM4EHPGDALDH1A1 | |
| SCHEMBL31488657 | 0.63 | CA12 (0.49) | CA12CA9KDM4EGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560898-B1 | PHOTOCHROMIC NAPHTHOPYRANS | PPG INDUSTRIES INC (US) | 1997-03-26 | — | — | EP | claimed |
| EP-0560898-A4 | PHOTOCHROMIC NAPHTHOPYRANS | — | 1993-11-18 | — | — | EP | claimed |
| EP-0560898-A1 | PHOTOCHROMIC NAPHTHOPYRANS. | PPG INDUSTRIES INC (US) | 1993-09-22 | — | — | EP | claimed |
| WO-1992009593-A1 | PHOTOCHROMIC NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1992-06-11 | — | — | WO | claimed |
| EP-0560898-B1 | PHOTOCHROMIC NAPHTHOPYRANS | PPG INDUSTRIES INC (US) | 1997-03-26 | — | — | EP | disclosed |
| US-5340857-A | Ophthalmic lenses, plastic transparencies | PPG INDUSTRIES, INC. (US) | 1994-08-23 | — | — | US | disclosed |
| EP-0560898-A4 | PHOTOCHROMIC NAPHTHOPYRANS | — | 1993-11-18 | — | — | EP | disclosed |
| EP-0560898-A1 | PHOTOCHROMIC NAPHTHOPYRANS. | PPG INDUSTRIES INC (US) | 1993-09-22 | — | — | EP | disclosed |
| US-5244602-A | Photochromic articles comprising polymerized organic host material and naphthopyran | PPG INDUSTRIES, INC. (US) | 1993-09-14 | — | — | US | disclosed |
| WO-1992009593-A1 | PHOTOCHROMIC NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1992-06-11 | — | — | WO | disclosed |