Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 10/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631529 | 0.92 | NPC1 (0.46) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL8631530 | 0.87 | MRGPRX4 (0.49) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL8630199 | 0.83 | MRGPRX4 (0.47) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL8631532 | 0.81 | MAOB (0.58) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL8378353 | 0.76 | MAOB (0.47) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL8378355 | 0.76 | MAOB (0.47) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL8632820 | 0.75 | NPC1 (0.47) | MRGPRX4SMN1; SMN2PKMRAB9ANPC1 | |
| SCHEMBL2518984 | 0.74 | MAPT (0.67) | SMN1; SMN2PKMMAPTTDP1L3MBTL1 | |
| SCHEMBL22178626 | 0.71 | MRGPRX4 (0.45) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| Amelubant SCHEMBL13696755 | 0.71 | MAOB (0.45) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731332-A | LEUKOTRIENE ANTAGONISTS; ANTIINFLAMMATORY AGENTS, ANTIALLERGENS | BOEHRINGER INGELHEIM KG (DE) | 1998-03-24 | — | — | US | claimed |
| US-5731332-A | LEUKOTRIENE ANTAGONISTS; ANTIINFLAMMATORY AGENTS, ANTIALLERGENS | BOEHRINGER INGELHEIM KG (DE) | 1998-03-24 | — | — | US | disclosed |