Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631530 | 0.88 | MRGPRX4 (0.49) | NPC1RAB9APKMSMN1; SMN2NR4A2 | |
| SCHEMBL8756345 | 0.83 | MAOB (0.63) | NPC1RAB9ASMN1; SMN2NR4A2MRGPRX4 | |
| SCHEMBL8631529 | 0.82 | NPC1 (0.46) | NPC1RAB9APKMSMN1; SMN2NR4A2 | |
| SCHEMBL8378348 | 0.81 | F2 (0.51) | NPC1RAB9APKMSMN1; SMN2NR4A2 | |
| Hydrochloric Acid SCHEMBL8756303 | 0.81 | RAB9A (0.52) | NPC1RAB9APKMSMN1; SMN2KDM4E | |
| SCHEMBL8378347 | 0.81 | F2 (0.51) | NPC1RAB9APKMSMN1; SMN2NR4A2 | |
| SCHEMBL1681364 | 0.79 | SMN1; SMN2 (0.60) | NPC1RAB9ASMN1; SMN2NR4A2MAOB | |
| SCHEMBL13450181 | 0.78 | MAOB (0.51) | NPC1RAB9APKMSMN1; SMN2NR4A2 | |
| SCHEMBL10013799 | 0.78 | LMNA (0.60) | NPC1RAB9ASMN1; SMN2NR4A2MAOB | |
| SCHEMBL6553509 | 0.77 | MAOB (0.54) | RAB9AMRGPRX4MAOBFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731332-A | LEUKOTRIENE ANTAGONISTS; ANTIINFLAMMATORY AGENTS, ANTIALLERGENS | BOEHRINGER INGELHEIM KG (DE) | 1998-03-24 | — | — | US | disclosed |