Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 2/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16359211 | 0.83 | CYP4F2 (0.49) | CYP4F2CYP4A11HTTCYP1A2CPB2 | |
| SCHEMBL8633101 | 0.81 | FDPS (0.42) | HTTCYP1A2CPB2THRBMEN1 | |
| SCHEMBL15317960 | 0.79 | CYP1A2 (0.47) | CYP4F2CYP4A11HTTCYP1A2CPB2 | |
| SCHEMBL6389074 | 0.79 | CYP4F2 (0.68) | CYP4F2CYP4A11HTTCYP1A2CPB2 | |
| SCHEMBL6593255 | 0.78 | CYP4F2 (0.47) | CYP4F2CYP4A11HTTCYP1A2CPB2 | |
| SCHEMBL8847004 | 0.76 | MEN1 (0.57) | CYP4F2CYP4A11HTTPKMTHRB | |
| SCHEMBL8979106 | 0.75 | MEN1 (0.53) | CYP4F2CYP4A11HTTCYP1A2CPB2 | |
| SCHEMBL29012390 | 0.74 | CYP1A2 (0.42) | CYP4F2CYP4A11HTTCYP1A2CPB2 | |
| SCHEMBL25169854 | 0.73 | CYP1A2 (0.48) | CYP4F2CYP4A11HTTCYP1A2CPB2 | |
| SCHEMBL22519815 | 0.73 | CYP4F2 (0.65) | CYP4F2CYP4A11HTTCYP1A2CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| EP-0667850-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS. | DOMPE FARMACEUTICI SPA (IT) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |