SCHEMBL8633101

SCHEMBL8633101

COC(=O)C(O)(CCCCCCN)C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 3/20 0.42
PAOX Q6QHF9 4/20 0.39
LMNA P02545 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
PLG P00747 1/20 0.35
THRB P10828 1/20 0.35
ALOX15 P16050 1/20 0.35
SLC6A2 P23975 1/20 0.35
RECQL P46063 1/20 0.35
SLC6A3 Q01959 1/20 0.35
KMT2A Q03164 1/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
HTT P42858 1/20 0.33
PDE3A Q14432 1/20 0.32
CYP2D6 P10635 1/20 0.32
NFKB1 P19838 1/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633741 0.92 FDPS (0.39) FDPSPAOXLMNATHRBKMT2A
SCHEMBL8629503 0.85 LMNA (0.36) FDPSLMNAALDH1A1PDE3ATSHR
SCHEMBL8630438 0.81 CYP4F2 (0.47) FDPSPAOXMEN1THRBALOX15
SCHEMBL9128079 0.80 CYP4F2 (0.46) FDPSPAOXLMNAMEN1ALDH1A1
SCHEMBL8987148 0.78 CYP4F2 (0.43) FDPSPAOXLMNAMEN1ALDH1A1
SCHEMBL31325597 0.76 ARG1 (0.39) FDPSPAOXLMNAMEN1ALDH1A1
SCHEMBL10795734 0.74 PKM (0.41) FDPSPAOXMEN1ALDH1A1THRB
SCHEMBL27537431 0.74 FDPS (0.48) FDPSPAOXLMNAMEN1ALDH1A1
SCHEMBL27593964 0.73 ODC1 (0.38) FDPSPAOXLMNATHRBKMT2A
SCHEMBL6652758 0.73 PAOX (0.37) FDPSPAOXLMNATHRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5773465-A Tartronic acids, their acetalic ethers and o-esters DOMPE FARMACEUTICI S.P.A. (IT) 1998-06-30 US disclosed
US-5656656-A Tartronic acids, their acetalic ethers and O-esters DOMPE FARMACEUTICI S.P.A. (IT) 1997-08-12 US disclosed
EP-0667850-B1 TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS DOMPE FARMACEUTICI SPA (IT) 1997-05-28 EP disclosed
EP-0667850-A1 TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS. DOMPE FARMACEUTICI SPA (IT) 1995-08-23 EP disclosed
WO-1994010127-A1 TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS DOMPE' FARMACEUTICI S.P.A. (IT) 1994-05-11 WO disclosed