SCHEMBL8630472

SCHEMBL8630472

COC(=O)[C@@](O)(CCC1CCCN1)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.34
CHRNA3 P32297 2/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNA4 P43681 1/20 0.34
CHRNB3 Q05901 1/20 0.34
CHRNA6 Q15825 1/20 0.34
KCNN4 O15554 1/20 0.32
DRD2 P14416 2/20 0.32
DRD3 P35462 2/20 0.32
GHSR Q92847 1/20 0.32
CHRNB4 P30926 1/20 0.31
MEN1 O00255 1/20 0.31
MITF O75030 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
ALOX15 P16050 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8636632 1.00 FDPS (0.34) FDPSCHRNA3CHRNB2CHRNA4CHRNB3
SCHEMBL8630698 1.00 FDPS (0.34) FDPSCHRNA3CHRNB2CHRNA4CHRNB3
SCHEMBL8630841 0.96 FDPS (0.39) FDPSGHSRMEN1MITFLMNA
SCHEMBL8633002 0.96 FDPS (0.39) FDPSGHSRMEN1MITFLMNA
SCHEMBL8630836 0.96 FDPS (0.39) FDPSGHSRMEN1MITFLMNA
SCHEMBL8630445 0.82 SLC6A2 (0.38) FDPSKCNN4GHSRMEN1MITF
SCHEMBL8630448 0.82 SLC6A2 (0.38) FDPSKCNN4GHSRMEN1MITF
SCHEMBL27534493 0.82 FDPS (0.46) FDPSGHSRMEN1MITFLMNA
SCHEMBL8632890 0.79 SLC6A1 (0.36) ALOX15SMN1; SMN2
SCHEMBL8632633 0.79 SLC6A1 (0.36) ALOX15SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5773465-A Tartronic acids, their acetalic ethers and o-esters DOMPE FARMACEUTICI S.P.A. (IT) 1998-06-30 US disclosed
US-5656656-A Tartronic acids, their acetalic ethers and O-esters DOMPE FARMACEUTICI S.P.A. (IT) 1997-08-12 US disclosed
EP-0667850-B1 TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS DOMPE FARMACEUTICI SPA (IT) 1997-05-28 EP disclosed
EP-0667850-A1 TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS. DOMPE FARMACEUTICI SPA (IT) 1995-08-23 EP disclosed
WO-1994010127-A1 TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS DOMPE' FARMACEUTICI S.P.A. (IT) 1994-05-11 WO disclosed