Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 12/20 | 0.53 |
| ▸ | PYGL | P06737 | 12/20 | 0.53 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GALK1 | P51570 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27946716 | 0.88 | POLB (0.54) | PYGMPYGLHPSEPOLBKDM4E | |
| SCHEMBL27994019 | 0.87 | PYGM (0.54) | PYGMPYGLHPSEPOLBKDM4E | |
| SCHEMBL11059819 | 0.85 | POLB (0.59) | PYGMPYGLHPSEPOLBKDM4E | |
| SCHEMBL8627947 | 0.82 | POLB (0.51) | PYGMPYGLHPSEPOLBKDM4E | |
| SCHEMBL8671721 | 0.82 | HPSE (0.49) | PYGMPYGLHPSEPOLBKDM4E | |
| SCHEMBL8671716 | 0.81 | HPSE (0.48) | PYGMPYGLHPSEPOLBKDM4E | |
| SCHEMBL7969637 | 0.81 | POLB (0.65) | PYGMPYGLHPSEPOLBKDM4E | |
| SCHEMBL29664286 | 0.81 | POLB (0.65) | PYGMPYGLHPSEPOLBKDM4E | |
| SCHEMBL8628620 | 0.80 | LPAR1 (0.58) | — | |
| SCHEMBL7627578 | 0.80 | GALK1 (0.51) | PYGMPYGLHPSEPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757702-B1 | POLY (IMIDE-ETHERS) | DU PONT (US) | 1998-07-01 | — | — | EP | disclosed |
| US-5675020-A | CHEMICAL INTERMEDIATES FOR PREPARING AROMATIC POLYIMIDES | THE UNIVERSITY OF LIVERPOOL (GB) | 1997-10-07 | — | — | US | disclosed |
| US-5434240-A | Films. fibers, encapsulation, thermoplastics | THE UNIVERSITY OF LIVERPOOL (GB) | 1995-07-18 | — | — | US | disclosed |