SCHEMBL8628620

SCHEMBL8628620

O=C(O)c1ccc(Oc2cccc(F)c2Oc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 16/20 0.58
LPAR5 Q9H1C0 16/20 0.58
PARP10 Q53GL7 1/20 0.54
SRD5A2 P31213 1/20 0.49
TTR P02766 1/20 0.49
HPGD P15428 1/20 0.48
HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL505520 0.90 LPAR1 (0.68) LPAR1LPAR5PARP10SRD5A2TTR
SCHEMBL3135333 0.85 LPAR1 (0.56) LPAR1LPAR5PARP10SRD5A2TTR
SCHEMBL3133651 0.85 PARP10 (0.73) LPAR1LPAR5PARP10SRD5A2
SCHEMBL16506673 0.83 LPAR1 (0.63) LPAR1LPAR5PARP10SRD5A2TTR
SCHEMBL16506793 0.83 LPAR1 (0.71) LPAR1LPAR5PARP10SRD5A2TTR
SCHEMBL8626752 0.81 LPAR1 (0.58) LPAR1LPAR5PARP10SRD5A2TTR
SCHEMBL8630499 0.80 PYGM (0.53)
SCHEMBL7706043 0.79 SRD5A2 (0.68) LPAR1LPAR5PARP10SRD5A2TTR
SCHEMBL23908714 0.78 RXRA (0.51) LPAR1LPAR5PARP10SRD5A2TTR
Hydrochloric Acid SCHEMBL8433842 0.77 SRD5A2 (0.66) LPAR1LPAR5PARP10SRD5A2TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0757702-B1 POLY (IMIDE-ETHERS) DU PONT (US) 1998-07-01 EP disclosed
US-5675020-A CHEMICAL INTERMEDIATES FOR PREPARING AROMATIC POLYIMIDES THE UNIVERSITY OF LIVERPOOL (GB) 1997-10-07 US disclosed
US-5434240-A Films. fibers, encapsulation, thermoplastics THE UNIVERSITY OF LIVERPOOL (GB) 1995-07-18 US disclosed