Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.41 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7704585 | 0.84 | — | — | |
| Acetic Acid SCHEMBL11454635 | 0.81 | CACNA2D1 (0.46) | FFAR3LCKFYNGABRR1CACNA2D1 | |
| Acetic Acid SCHEMBL28858092 | 0.81 | ALDH1A1 (0.62) | FFAR3LCKFYNGABRR1CACNA2D1 | |
| Acetic Acid SCHEMBL3336394 | 0.81 | ALDH1A1 (0.62) | FFAR3LCKFYNGABRR1CACNA2D1 | |
| Acetic Acid SCHEMBL8817349 | 0.81 | — | — | |
| Acetic Acid SCHEMBL21227 | 0.81 | ALDH1A1 (0.62) | FFAR3LCKFYNGABRR1CACNA2D1 | |
| Acetic Acid SCHEMBL2678979 | 0.81 | — | — | |
| Acetic Acid SCHEMBL6150069 | 0.81 | ALDH1A1 (0.62) | FFAR3LCKFYNGABRR1CACNA2D1 | |
| Acetic Acid SCHEMBL12474237 | 0.81 | ALDH1A1 (0.62) | FFAR3LCKFYNGABRR1CACNA2D1 | |
| Acetic Acid SCHEMBL27861656 | 0.81 | FFAR3 (0.44) | FFAR3LCKFYNGABRR1CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540990-B1 | Tablet-shaped processing agent and method for processing silver halide photographic light sensitive materials | KONISHIROKU PHOTO IND (JP) | 1998-07-15 | — | — | EP | disclosed |
| US-5366853-A | Bleaches for photographic films | KONICA CORPORATION (JP) | 1994-11-22 | — | — | US | disclosed |
| US-5362610-A | Photographic processing agent | KONICA CORPORATION (JP) | 1994-11-08 | — | — | US | disclosed |
| EP-0540990-A1 | Tablet-shaped processing agent and method for processing silver halide photographic light sensitive materials | KONICA CORPORATION (JP) | 1993-05-12 | — | — | EP | disclosed |
| EP-0540296-A1 | Photographic processing agent | KONICA CORPORATION (JP) | 1993-05-05 | — | — | EP | disclosed |