Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Formaldehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL912817 | 0.96 | LMNA (0.59) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| Potassium Ion SCHEMBL30466771 | 0.96 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| Potassium Ion SCHEMBL3843865 | 0.96 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| Potassium Ion SCHEMBL30466772 | 0.96 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL587370 | 0.91 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL9888371 | 0.91 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL12234418 | 0.91 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL1588805 | 0.91 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| Lithium Ion SCHEMBL1457859 | 0.91 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL29368068 | 0.91 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583443-B1 | MAKING FLOWABLE ALKALI OR AMMONIUM THIOSULFATE OR SULFITE AND ITS PRODUCT-BY-PROCESS | FUJI HUNT PHOTO CHEM (BE) | 1998-11-04 | — | — | EP | disclosed |
| US-RE35795-E | PHOTOGRAPHIC FIXATIVES | FUJI HUNT PHOTOGRAPHIC CHEMICALS, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| EP-0583443-A4 | MAKING FLOWABLE ALKALI OR AMMONIUM THIOSULFATE OR SULFITE AND ITS PRODUCT-BY-PROCESS | FUJI HUNT PHOTO CHEM (BE) | 1994-07-27 | — | — | EP | disclosed |
| US-5328814-A | Containing a dry alkali metal arylsulfonate.formaldehyde | FUJI HUNT PHOTOGRAPHIC CHEMICALS, INC. (US) | 1994-07-12 | — | — | US | disclosed |
| EP-0583443-A1 | MAKING FLOWABLE ALKALI OR AMMONIUM THIOSULFATE OR SULFITE AND ITS PRODUCT-BY-PROCESS | FUJI HUNT PHOTOGRAPHIC CHEMICALS, N.V. (BE) | 1994-02-23 | — | — | EP | disclosed |
| US-5270154-A | Method of making flowable alkaline thiosulfate/alkaline sulfite and the product thereof | FUJI HUNT PHOTOGRAPHIC CHEMICALS INC. (US) | 1993-12-14 | — | — | US | disclosed |
| WO-1993015437-A1 | MAKING FLOWABLE ALKALI OR AMMONIUM THIOSULFATE OR SULFITE AND ITS PRODUCT-BY-PROCESS | FUJI HUNT PHOTOGRAPHIC CHEMICALS, INC. (US) | 1993-08-05 | — | — | WO | disclosed |