Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630480 | 0.92 | PTGS2 (0.43) | PTGS2PTGS1F10PI4KBF2 | |
| SCHEMBL8629097 | 0.89 | PTGS2 (0.45) | PTGS2PTGS1F10F2 | |
| SCHEMBL7777495 | 0.89 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL8635624 | 0.88 | PTGS2 (0.45) | PTGS2PTGS1F10P2RX3PI4KB | |
| SCHEMBL8632811 | 0.85 | PTGS2 (0.43) | PTGS2PTGS1F10P2RX3PI4KB | |
| SCHEMBL8632921 | 0.85 | PTGS2 (0.46) | PTGS2PTGS1F10P2RX3PI4KB | |
| SCHEMBL8630564 | 0.85 | PTGS2 (0.45) | PTGS2PTGS1F10PI4KBF2 | |
| SCHEMBL8632828 | 0.85 | PTGS2 (0.49) | PTGS2PTGS1F10P2RX3F2 | |
| SCHEMBL8634717 | 0.85 | PTGS2 (0.43) | PTGS2PTGS1F10P2RX3PI4KB | |
| SCHEMBL7780078 | 0.84 | PTGS2 (0.64) | PTGS2PTGS1PI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |