Diacetamate

Diacetamate

SCHEMBL863106

CC(=O)Nc1ccc(OC(C)=O)cc1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.81
MEN1 O00255 5/20 0.81
NPSR1 Q6W5P4 1/20 0.68
ALDH1A1 P00352 4/20 0.62
MAPT P10636 3/20 0.62
SMN1; SMN2 Q16637 4/20 0.62
HSD17B10 Q99714 2/20 0.62
GAA P10253 2/20 0.61
LMNA P02545 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
HSP90AA1 P07900 1/20 0.61
CYP1A2 P05177 1/20 0.61
HTT P42858 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
HPGD P15428 2/20 0.58
OPRK1 P41145 1/20 0.58
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA9 Q16790 2/20 0.58
TSHR P16473 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8579105 0.94 KMT2A (0.72) KMT2AMEN1NPSR1ALDH1A1MAPT
SCHEMBL14808444 0.89 KMT2A (1.00) KMT2AMEN1NPSR1ALDH1A1MAPT
SCHEMBL3681053 0.88 KMT2A (0.75) KMT2AMEN1NPSR1ALDH1A1MAPT
SCHEMBL11414849 0.88 KMT2A (0.66) KMT2AMEN1NPSR1ALDH1A1MAPT
SCHEMBL25046378 0.84 MEN1 (0.58) KMT2AMEN1NPSR1ALDH1A1MAPT
SCHEMBL8264218 0.84 ALDH1A1 (0.61) KMT2AMEN1NPSR1ALDH1A1MAPT
SCHEMBL12291744 0.84 KMT2A (0.75) KMT2AMEN1NPSR1ALDH1A1MAPT
SCHEMBL14645413 0.84 KMT2A (0.75) KMT2AMEN1NPSR1ALDH1A1MAPT
SCHEMBL1404254 0.84 KMT2A (0.75) KMT2AMEN1NPSR1ALDH1A1MAPT
SCHEMBL3676589 0.84 SMN1; SMN2 (0.66) KMT2AMEN1NPSR1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 380 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115872885-B Preparation method of acetaminophen with controlled content of acetaminophen impurity N 河北冀衡药业股份有限公司 2024-10-18 CN claimed
CN-117347533-B Method for detecting related substances of compound paracetamol and renin tablets for children 山东则正医药技术有限公司 2024-04-19 CN claimed
CN-117347533-A Method for detecting related substances of compound paracetamol and renin tablets for children 山东则正医药技术有限公司 2024-01-05 CN claimed
CN-115894271-A Preparation method of acetaminophen by controlling content of acetaminophen impurity H 河北冀衡药业股份有限公司 2023-04-04 CN claimed
CN-115872885-A Preparation method of acetaminophen by controlling content of acetaminophen impurity N 河北冀衡药业股份有限公司 2023-03-31 CN claimed
WO-2022228297-A1 ENZYMATIC PREPARATION TECHNIQUE FOR ACYL/AROYL COENZYME A 中国医学科学院药物研究所 2022-11-03 WO claimed
CN-115247192-A Enzymatic preparation technology of acyl/aroyl coenzyme A 中国医学科学院药物研究所 2022-10-28 CN claimed
CN-113299918-B Negative pole piece and lithium ion battery comprising same 珠海冠宇动力电池有限公司 2022-07-15 CN claimed
CN-113300048-B Diaphragm and lithium ion battery comprising same 珠海冠宇动力电池有限公司 2022-07-15 CN claimed
CN-113299919-B Positive pole piece and lithium ion battery comprising same 珠海冠宇动力电池有限公司 2022-07-12 CN claimed
EP-0352845-B1 A process for the preparation of aromatic thermotropic copolyesteramides,and copolyesteramides corresponding thereto. CABLES DE COMUNICACIONES, S.A. (ES) 1993-02-03 EP claimed
EP-0429127-A1 Thermotropic copolyesteramide, process for its preparation and utilization ENIRICERCHE S.p.A. (IT) 1991-05-29 EP claimed
EP-0194849-B1 IMPROVED PROCESS FOR PRODUCING N-ACYL-ACYLOXY AROMATIC AMINES CELANESE CORPORATION (US) 1990-10-03 EP claimed
EP-0352845-A1 A process for the preparation of aromatic thermotropic copolyesteramides,and copolyesteramides corresponding thereto. CABLES DE COMUNICACIONES, S.A. (ES) 1990-01-31 EP claimed
EP-0168908-B1 PROCESS FOR PRODUCING N-ACYL-ACYLOXY AROMATIC AMINES CELANESE CORPORATION (US) 1988-12-07 EP claimed
US-4665216-A Process for producing n-acyl-acyloxy aromatic amines CELANESE CORPORATION (US) 1987-05-12 US claimed
EP-0194849-A2 Improved process for producing N-acyl-acyloxy aromatic amines CELANESE CORPORATION (US) 1986-09-17 EP claimed
US-4568763-A Process for producing N-acyl-acyloxy aromatic amines CELANESE CORPORATION (US) 1986-02-04 US claimed
EP-0168908-A1 Process for producing N-acyl-acyloxy aromatic amines CELANESE CORPORATION (US) 1986-01-22 EP claimed
US-4560789-A Process for producing 4-acetoxyacetanilide CELANESE CORPORATION (US) 1985-12-24 US claimed