Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5235403 | 0.85 | SMN1; SMN2 (0.66) | SMN1; SMN2HPGDMEN1KMT2AGAA | |
| Diacetamate SCHEMBL863106 | 0.84 | KMT2A (0.81) | SMN1; SMN2HPGDMEN1KMT2AGAA | |
| SCHEMBL9609808 | 0.83 | SMN1; SMN2 (0.82) | SMN1; SMN2HPGDKMT2AGAAALDH1A1 | |
| SCHEMBL12893240 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2HPGDMEN1KMT2AGAA | |
| SCHEMBL1162988 | 0.82 | LIPE (0.52) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL11773292 | 0.82 | SMN1; SMN2 (0.85) | SMN1; SMN2HPGDGAAALDH1A1MAPT | |
| SCHEMBL2089394 | 0.82 | SMN1; SMN2 (0.73) | SMN1; SMN2HPGDMEN1KMT2AGAA | |
| SCHEMBL10780962 | 0.81 | ALDH1A1 (0.81) | SMN1; SMN2HPGDMEN1KMT2AGAA | |
| SCHEMBL25046378 | 0.81 | MEN1 (0.58) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL8264218 | 0.81 | ALDH1A1 (0.61) | MEN1KMT2AGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2400846-B1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARM INC (US) | 2016-10-05 | — | — | EP | disclosed |
| CN-102427731-B | Hepatitis c virus inhibitors | ENANTA PHARM INC | 2015-05-13 | — | — | CN | disclosed |
| US-8507522-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| CN-102427731-A | Hepatitis c virus inhibitors | ENANTA PHARM INC | 2012-04-25 | — | — | CN | disclosed |
| US-20100260715-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100260715-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, SLC10A1, EIF2AK2 | SMN1; SMN2 4162/4885HPGD 1806/4885MEN1 4782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.