Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632186 | 0.90 | CA1 (0.51) | PTGS2PTGS1ALDH1A1LMNACA12 | |
| SCHEMBL8167385 | 0.87 | PTGS2 (0.48) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL8180054 | 0.85 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL8175595 | 0.84 | CDC25B (0.54) | PTGS2PTGS1ALDH1A1LMNACA12 | |
| SCHEMBL7772868 | 0.83 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL7779606 | 0.82 | PTGS2 (0.50) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL7777941 | 0.81 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL8175431 | 0.80 | ALDH1A1 (0.43) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL7779971 | 0.78 | CNR1 (0.46) | PTGS2PTGS1ALDH1A1CA1CA2 | |
| SCHEMBL8179843 | 0.77 | CA1 (0.55) | PTGS2PTGS1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |
| US-5486534-A | 3,4-substituted pyrazoles for the treatment of inflammation | G. D. SEARLE & CO. (US) | 1996-01-23 | — | — | US | disclosed |