Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NAT1 | P18440 | 1/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629108 | 0.88 | EDNRB (0.47) | KDM1AMAPTNPSR1MAPK1MEN1 | |
| SCHEMBL8633966 | 0.84 | KDM1A (0.49) | KDM1AMAPTNPSR1MAPK1MEN1 | |
| SCHEMBL8627790 | 0.83 | MAPT (0.45) | KDM1AMAPTNPSR1MAPK1MEN1 | |
| SCHEMBL8632291 | 0.81 | KDM1A (0.46) | KDM1AMAPTNPSR1MAPK1MEN1 | |
| SCHEMBL8635070 | 0.79 | KDM1A (0.49) | KDM1AMAPTNPSR1MAPK1MEN1 | |
| SCHEMBL8632682 | 0.79 | KDM1A (0.46) | KDM1AMAPTNPSR1MAPK1MEN1 | |
| SCHEMBL8631594 | 0.78 | KDM1A (0.46) | KDM1AMAPTNPSR1MAPK1MEN1 | |
| SCHEMBL8635015 | 0.77 | KDM1A (0.45) | KDM1AMAPTNPSR1MAPK1MEN1 | |
| SCHEMBL8627973 | 0.74 | KDM1A (0.51) | KDM1AMAPTNPSR1MAPK1MEN1 | |
| SCHEMBL8632313 | 0.73 | SMN1; SMN2 (0.58) | KDM1AMAPTMEN1KMT2ANAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |