Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.45 |
| ▸ | NAT1 | P18440 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | EDNRB | P24530 | 2/20 | 0.40 |
| ▸ | EDNRA | P25101 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | S100A9 | P06702 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632682 | 0.91 | KDM1A (0.46) | KDM1ANAT1POLBALDH1A1NPSR1 | |
| SCHEMBL8631594 | 0.90 | KDM1A (0.46) | KDM1ANAT1POLBALDH1A1NPSR1 | |
| SCHEMBL8628161 | 0.89 | CA12 (0.41) | POLBEDNRAMAPTKDM4ELMNA | |
| SCHEMBL8629976 | 0.82 | L3MBTL1 (0.51) | ALDH1A1NPSR1EDNRBEDNRAMAPT | |
| SCHEMBL8631355 | 0.80 | L3MBTL1 (0.44) | POLBNPSR1EDNRBEDNRAMAPT | |
| SCHEMBL8633966 | 0.80 | KDM1A (0.49) | KDM1ANAT1POLBALDH1A1NPSR1 | |
| SCHEMBL8630569 | 0.80 | MEN1 (0.43) | POLBNPSR1MAPTKDM4ERXFP1 | |
| SCHEMBL8635392 | 0.79 | L3MBTL1 (0.49) | POLBALDH1A1NPSR1EDNRBEDNRA | |
| SCHEMBL8629853 | 0.79 | MEN1 (0.45) | ALDH1A1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL8635070 | 0.79 | KDM1A (0.49) | KDM1ANAT1POLBALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |