Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.51 |
| ▸ | NAT1 | P18440 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | EDNRB | P24530 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632286 | 0.90 | KIT (0.45) | ALDH1A1NPSR1KDM4ERXFP1LMNA | |
| SCHEMBL8632837 | 0.86 | LMNA (0.51) | POLBALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL8632960 | 0.86 | KEAP1 (0.51) | POLBALDH1A1NPSR1KDM4ELMNA | |
| SCHEMBL8634763 | 0.86 | NAT1 (0.45) | NAT1ALDH1A1NPSR1KDM4ERXFP1 | |
| SCHEMBL8631178 | 0.86 | STAT3 (0.47) | POLBNPSR1KDM4ERXFP1LMNA | |
| SCHEMBL8631080 | 0.86 | KMO (0.52) | KDM1ANPSR1KDM4ERXFP1MEN1 | |
| SCHEMBL8631659 | 0.86 | NAT1 (0.53) | KDM1ANAT1NPSR1KDM4ERXFP1 | |
| SCHEMBL8630955 | 0.85 | IMPDH2 (0.54) | NPSR1KDM4ERXFP1LMNAKIT | |
| SCHEMBL8632208 | 0.84 | STAT3 (0.51) | POLBALDH1A1LMNAKMT2APGR | |
| SCHEMBL8629389 | 0.83 | ERBB2 (0.45) | NAT1POLBALDH1A1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |