Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GYS1 | P13807 | 7/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629979 | 0.91 | GYS1 (0.58) | GYS1LRRK2MAPTGPR55CNR1 | |
| SCHEMBL8635394 | 0.91 | LRRK2 (0.49) | GYS1LRRK2MAPTGPR55CNR1 | |
| SCHEMBL8633593 | 0.89 | MAPT (0.51) | GYS1LRRK2MAPTGPR55CNR1 | |
| SCHEMBL8632688 | 0.89 | GYS1 (0.58) | GYS1LRRK2MAPTGPR55CNR1 | |
| SCHEMBL8629857 | 0.89 | LRRK2 (0.48) | GYS1LRRK2MAPTGPR55CNR1 | |
| SCHEMBL8628834 | 0.88 | LRRK2 (0.60) | GYS1LRRK2MAPTGPR55CNR1 | |
| SCHEMBL8634944 | 0.87 | LRRK2 (0.49) | GYS1LRRK2MAPTGPR55CNR1 | |
| SCHEMBL8627994 | 0.86 | LRRK2 (0.46) | GYS1LRRK2MAPTGPR55CNR1 | |
| SCHEMBL8633703 | 0.86 | MAPT (0.60) | GYS1LRRK2MAPTGPR55CNR1 | |
| SCHEMBL8631700 | 0.86 | TRPV1 (0.47) | GYS1LRRK2MAPTGPR55CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |