Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.60 |
| ▸ | CNR1 | P21554 | 2/20 | 0.60 |
| ▸ | CNR2 | P34972 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.46 |
| ▸ | CDK4 | P11802 | 3/20 | 0.46 |
| ▸ | CCND1 | P24385 | 3/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.46 |
| ▸ | CDK2 | P24941 | 3/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GYS1 | P13807 | 2/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627680 | 0.89 | MAPT (0.47) | MAPTGPR55CNR1CNR2ALDH1A1 | |
| SCHEMBL8631700 | 0.89 | TRPV1 (0.47) | MAPTGPR55CNR1CNR2ALDH1A1 | |
| SCHEMBL8629857 | 0.88 | LRRK2 (0.48) | MAPTGPR55CNR1CNR2ALDH1A1 | |
| SCHEMBL8629979 | 0.87 | GYS1 (0.58) | MAPTGPR55CNR1CNR2ALDH1A1 | |
| SCHEMBL8631356 | 0.86 | GYS1 (0.57) | MAPTGPR55CNR1CNR2ALDH1A1 | |
| SCHEMBL8635394 | 0.86 | LRRK2 (0.49) | MAPTGPR55CNR1CNR2ALDH1A1 | |
| SCHEMBL8632688 | 0.85 | GYS1 (0.58) | MAPTGPR55CNR1CNR2BLM | |
| SCHEMBL8633593 | 0.85 | MAPT (0.51) | MAPTGPR55CNR1CNR2ALDH1A1 | |
| SCHEMBL8627994 | 0.85 | LRRK2 (0.46) | MAPTGPR55CNR1CNR2ALDH1A1 | |
| SCHEMBL8631668 | 0.85 | PTGS2 (0.50) | MAPTGPR55CNR1CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |