Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687699 | 0.78 | CYP3A4 (0.41) | MAPK1SLC6A3KDM4EPKMALDH1A1 | |
| SCHEMBL8690000 | 0.71 | KMT2A (0.39) | MAPK1SLC6A3KDM4EPKMALDH1A1 | |
| SCHEMBL7129049 | 0.71 | MAPK1 (0.55) | MAPK1CHRM2ALDH1A1ALOX15KMT2A | |
| SCHEMBL23618656 | 0.62 | AKT1 (0.40) | KDM4EALDH1A1ALOX15KMT2A | |
| SCHEMBL9576890 | 0.62 | MAPK1 (0.62) | MAPK1CHRM2ALDH1A1ALOX15KMT2A | |
| SCHEMBL679793 | 0.61 | KDM4E (0.53) | SLC6A3KDM4EPKMALDH1A1KMT2A | |
| SCHEMBL664301 | 0.60 | MAPK1 (0.52) | MAPK1ALDH1A1ALOX15KMT2A | |
| SCHEMBL3887648 | 0.60 | MAPK1 (0.46) | MAPK1CHRM2ALDH1A1ALOX15KMT2A | |
| SCHEMBL14292070 | 0.60 | MAPK1 (0.46) | MAPK1CHRM2ALDH1A1ALOX15KMT2A | |
| SCHEMBL22715431 | 0.60 | KDM4E (0.36) | KDM4EPKMALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712299-A | TREATMENT OF NEURODEGENERATIVE DISORDERS | ASTRA AKTIEBOLAG (SE) | 1998-01-27 | — | — | US | disclosed |