Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632879 | 0.90 | PTGS2 (0.58) | PTGS2PTGS1F10TRPV1 | |
| SCHEMBL8630025 | 0.89 | PTGS2 (0.58) | PTGS2PTGS1F10TRPV1CA12 | |
| SCHEMBL8629123 | 0.89 | PTGS2 (0.70) | PTGS2PTGS1F10TRPV1 | |
| SCHEMBL8630541 | 0.88 | PTGS2 (0.57) | PTGS2PTGS1F10 | |
| SCHEMBL8488736 | 0.87 | PTGS2 (0.55) | PTGS2PTGS1F10TRPV1PTGDR2 | |
| SCHEMBL8633059 | 0.86 | PTGS2 (0.55) | PTGS2PTGS1F10TRPV1PTGES2 | |
| SCHEMBL8634613 | 0.86 | PTGS2 (0.55) | PTGS2PTGS1F10 | |
| SCHEMBL7777824 | 0.83 | PTGS2 (0.78) | PTGS2PTGS1CNR1CA12CA1 | |
| SCHEMBL8632205 | 0.83 | PTGS2 (0.45) | PTGS2PTGS1F10CA12CA1 | |
| SCHEMBL8628841 | 0.82 | PTGS2 (0.43) | PTGS2PTGS1F10TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |