Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632780 | 0.84 | F10 (0.45) | HRH3F10TSHRLSSALDH1A1 | |
| SCHEMBL8695326 | 0.74 | F10 (0.41) | HRH3SMN1; SMN2F10TSHRMAPK1 | |
| SCHEMBL8683270 | 0.71 | F10 (0.44) | HRH3SMN1; SMN2F10TSHRMAPK1 | |
| SCHEMBL8790550 | 0.70 | HRH3 (0.46) | HRH3MAPTSMN1; SMN2TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL8631954 | 0.69 | CYP2C9 (0.42) | HRH3SMN1; SMN2F10TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL8683467 | 0.69 | F10 (0.43) | HRH3SMN1; SMN2F10TSHRMAPK1 | |
| SCHEMBL8633125 | 0.69 | F10 (0.52) | HRH3MAPTSMN1; SMN2F10LMNA | |
| Hydrochloric Acid SCHEMBL8636989 | 0.68 | ABCB1 (0.48) | HRH3RAB9ANPY2RPOLBALDH1A1 | |
| SCHEMBL8686293 | 0.68 | HRH3 (0.51) | HRH3MAPTSMN1; SMN2F10POLB | |
| SCHEMBL4435638 | 0.68 | ITGB3 (0.46) | HRH3TSHRLSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |