Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | LIPA | P38571 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5949903 | 0.98 | ALDH1A1 (0.41) | ALDH1A1HSD17B10GAAMAPK1HPGD | |
| SCHEMBL23000151 | 0.64 | ALDH1A1 (0.42) | ALDH1A1HSD17B10GAAMAPK1HPGD | |
| SCHEMBL971921 | 0.63 | USP2 (0.41) | ALDH1A1TSHRLMNATP53RAB9A | |
| SCHEMBL10399208 | 0.63 | ALDH1A1 (0.39) | ALDH1A1HSD17B10GAAMAPK1HPGD | |
| SCHEMBL21737951 | 0.62 | ALDH1A1 (0.61) | ALDH1A1HSD17B10GAAMAPK1SMN1; SMN2 | |
| SCHEMBL5631018 | 0.61 | ALDH1A1 (1.00) | ALDH1A1HSD17B10GAAMAPK1HPGD | |
| SCHEMBL8026243 | 0.61 | ALDH1A1 (0.44) | ALDH1A1HSD17B10GAAMAPK1HPGD | |
| SCHEMBL11372459 | 0.61 | ALDH1A1 (1.00) | ALDH1A1HSD17B10GAAMAPK1HPGD | |
| SCHEMBL23975594 | 0.61 | ALDH1A1 (0.59) | ALDH1A1HSD17B10GAAMAPK1HPGD | |
| SCHEMBL744777 | 0.61 | ALDH1A1 (0.39) | ALDH1A1HSD17B10GAAMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |