Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10064295 | 0.81 | CA12 (0.35) | LMNATDP1KDM4E | |
| SCHEMBL14394672 | 0.78 | TSHR (0.46) | LMNA | |
| SCHEMBL4747060 | 0.76 | CYP2C19 (0.50) | LMNA | |
| SCHEMBL24926041 | 0.74 | LMNA (0.42) | LMNA | |
| SCHEMBL10031128 | 0.74 | — | — | |
| SCHEMBL13123627 | 0.74 | — | — | |
| SCHEMBL24474076 | 0.68 | SIGMAR1 (0.32) | — | |
| SCHEMBL272858 | 0.67 | TDP1 (0.36) | LMNACNR1ADRA1ATDP1KDM4E | |
| Hydrochloric Acid SCHEMBL13859290 | 0.64 | ABCC3 (0.36) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL22546863 | 0.64 | CYP2C19 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773550-A | POLYESTERURETHANE COPOLYMERS WITH URETDIONE GROUPS | HUELS AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |
| EP-0790266-A1 | Isocyanurate and urethdione groups groups containing polyaddition products as well as a process for their preparation | HÜLS AKTIENGESELLSCHAFT (DE) | 1997-08-20 | — | — | EP | disclosed |
| EP-0650988-B1 | Cold curing, poorinsolvent or solventless 2-components polyurethane-urea composition | HUELS CHEMISCHE WERKE AG (DE) | 1997-05-21 | — | — | EP | disclosed |
| EP-0650988-A1 | Cold curing, poorinsolvent or solventless 2-components polyurethane-urea composition | HÜLS AKTIENGESELLSCHAFT (DE) | 1995-05-03 | — | — | EP | disclosed |
| EP-0321658-B1 | PROCESS FOR THE PREPARATION OF BLOCKED POLYISOCYANATES CONTAINING UREA GROUPS, AND PRODUCTS PREPARED THEREFROM | HÜLS AKTIENGESELLSCHAFT (DE) | 1993-06-16 | — | — | EP | disclosed |
| US-4925974-A | REACTING PARTIALLY BLOCKED POLYISOCYANATE WITH POLYAMINE; ISOLATING | HUELS AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |