Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456732 | 0.85 | KLK7 (0.52) | PPARAPPARGKLK7KLK5CACNA1B | |
| SCHEMBL5623452 | 0.85 | KLK7 (0.52) | PPARAPPARGKLK7KLK5CACNA1B | |
| SCHEMBL29402178 | 0.85 | KLK7 (0.53) | PPARAPPARGKLK7KLK5CACNA1B | |
| SCHEMBL19104158 | 0.85 | CACNA1B (0.53) | PPARAPPARGKLK7KLK5CACNA1B | |
| SCHEMBL14446364 | 0.84 | PPARA (0.56) | PPARAPPARGCACNA1BALDH1A1MAPT | |
| SCHEMBL4848380 | 0.84 | PPARA (0.50) | PPARAPPARGKLK7KLK5CACNA1B | |
| SCHEMBL28054337 | 0.84 | PPARA (0.61) | PPARAPPARGKLK7KLK5CACNA1B | |
| SCHEMBL1025258 | 0.84 | PPARA (0.50) | PPARAPPARGKLK7KLK5CACNA1B | |
| SCHEMBL28054294 | 0.84 | PPARA (0.61) | PPARAPPARGKLK7KLK5CACNA1B | |
| SCHEMBL31195279 | 0.82 | PPARA (0.56) | PPARAPPARGCACNA1BALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830864-A | RIBONUCLEOTIDE REDUCTASE INHIBITOR | BOEHRINGER INGELHEIM (CANADA), LTD. (CA) | 1998-11-03 | — | — | US | disclosed |
| EP-0560274-B1 | Antiherpes peptide derivatives having a ureido N-terminus | BOEHRINGER INGELHEIM CA LTD (CA) | 1998-06-24 | — | — | EP | disclosed |
| US-5700780-A | OLIGOPEPTIDE VIRICIDES; RIBONUCLEOTIDE REDUCTASE ENZYME INHIBITOR | BOEHRINGER INGELHEIM (CANADA), LTD. (CA) | 1997-12-23 | — | — | US | disclosed |
| EP-0493770-B1 | Antiherpes compositions | BOEHRINGER INGELHEIM CA LTD (CA) | 1997-08-06 | — | — | EP | disclosed |
| EP-0493767-B1 | Synergistic combination for treating herpes infections | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1997-03-19 | — | — | EP | disclosed |
| US-5552384-A | Antiherpes compositions and method of use | BIO-MEGA BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1996-09-03 | — | — | US | disclosed |
| US-5484771-A | RIBONUCLEOTIDE REDUCTASE INHIBITORS | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1996-01-16 | — | — | US | disclosed |
| EP-0411332-B1 | Antiviral peptides having a 2-oxoalkyl amino acid side chain | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-12-06 | — | — | EP | disclosed |
| EP-0461546-B1 | Antiherpes peptide derivatives having a 1,4-dioxo-C4 N-terminus | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-03-22 | — | — | EP | disclosed |
| US-5380727-A | Antiviral nucleoside analog and a ribonucleotide reductase inhibiting peptide derivative | BIO-MEGA, INC. (CA) | 1995-01-10 | — | — | US | disclosed |
| EP-0560274-A1 | Antiherpes peptide derivatives having a ureido N-terminus | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-15 | — | — | EP | disclosed |
| EP-0493767-A2 | Synergistic combination for treating herpes infections | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1992-07-08 | — | — | EP | disclosed |
| EP-0493770-A2 | Antiherpes compositions | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1992-07-08 | — | — | EP | disclosed |
| EP-0461546-A2 | Antiherpes peptide derivatives having a 1,4-dioxo-C4 N-terminus | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1991-12-18 | — | — | EP | disclosed |
| EP-0411332-A1 | Antiviral peptides having a 2-oxoalkyl amino acid side chain | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1991-02-06 | — | — | EP | disclosed |