SCHEMBL1025258

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4848380	1.00	PPARA (0.50)	PPARAKLK7KLK5PPARGCACNA1B
	SCHEMBL8632310	0.84	PPARA (0.53)	PPARAKLK7KLK5PPARGCACNA1B
	SCHEMBL5033775	0.84	PPARA (0.58)	PPARAKLK7KLK5PPARGCACNA1B
	SCHEMBL3004720	0.84	PPARA (0.58)	PPARAKLK7KLK5PPARGCACNA1B
	SCHEMBL1093029	0.84	PPARA (0.58)	PPARAKLK7KLK5PPARGCACNA1B
	SCHEMBL19104158	0.83	CACNA1B (0.53)	PPARAKLK7KLK5PPARGCACNA1B
	SCHEMBL4370045	0.83	KLK5 (0.65)	PPARAKLK7KLK5PPARGCACNA1B
	SCHEMBL14211452	0.83	PPARA (0.57)	PPARAKLK7KLK5PPARGCACNA1B
	SCHEMBL14002405	0.83	CPA1 (0.51)	CTSLCTSBTACR1CPA1ACE
	SCHEMBL4854926	0.83	PPARA (0.50)	PPARAKLK7KLK5PPARGCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.