Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907962 | 0.86 | GPR84 (0.43) | GPR84NQO1KMT2AL3MBTL1RAB9A | |
| SCHEMBL7907955 | 0.82 | GPR84 (0.42) | GPR84NQO1L3MBTL1RAB9AMAPT | |
| SCHEMBL8110627 | 0.77 | NQO1 (0.50) | GPR84NQO1SLC5A1SLC5A2LMNA | |
| SCHEMBL8990694 | 0.72 | NQO1 (0.52) | NQO1KMT2AL3MBTL1RAB9AMAPT | |
| SCHEMBL8990660 | 0.72 | NQO1 (0.52) | NQO1KMT2AL3MBTL1RAB9AMAPT | |
| SCHEMBL8095387 | 0.71 | KMT2A (0.41) | GPR84NQO1KMT2ARAB9ASLC5A1 | |
| SCHEMBL8990956 | 0.71 | KMT2A (0.49) | GPR84NQO1KMT2AL3MBTL1RAB9A | |
| SCHEMBL28616323 | 0.71 | NQO1 (0.74) | GPR84NQO1SLC5A1SLC5A2LMNA | |
| SCHEMBL8449278 | 0.71 | GPR84 (0.44) | GPR84NQO1KMT2ASLC5A1SLC5A2 | |
| SCHEMBL9664359 | 0.71 | FFAR1 (0.51) | GPR84NQO1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449015-B1 | Difluoromethyl compounds and liquid criystal medium | MERCK PATENT GMBH (DE) | 1998-07-01 | — | — | EP | disclosed |
| EP-0449015-A2 | Difluoromethyl compounds and liquid criystal medium | MERCK PATENT GmbH (DE) | 1991-10-02 | — | — | EP | disclosed |