Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.51 |
| ▸ | PPARD | Q03181 | 4/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063154 | 0.88 | CYP17A1 (0.46) | FFAR1PPARDCYP17A1S1PR1RXRA | |
| SCHEMBL14766297 | 0.87 | FFAR1 (0.42) | FFAR1PPARDCYP17A1S1PR1PPARG | |
| SCHEMBL11067272 | 0.85 | RARB (0.51) | FFAR1PPARDCYP17A1S1PR1PPARA | |
| SCHEMBL14766468 | 0.85 | FFAR1 (0.42) | FFAR1PPARDNQO1CALM1PPARG | |
| SCHEMBL18310399 | 0.84 | FFAR1 (0.50) | FFAR1PPARDCYP17A1NQO1KDM1A | |
| SCHEMBL10976808 | 0.84 | CYP17A1 (0.48) | FFAR1PPARDCYP17A1S1PR1RXRA | |
| SCHEMBL9512344 | 0.84 | RARB (0.57) | CYP17A1S1PR1RXRARXRBRXRG | |
| SCHEMBL9512933 | 0.84 | RARB (0.57) | CYP17A1S1PR1RXRARXRBRXRG | |
| SCHEMBL9484876 | 0.83 | L3MBTL1 (0.53) | FFAR1PPARDCYP17A1RXRARXRB | |
| SCHEMBL20803720 | 0.83 | GABRA1 (0.40) | FFAR1PPARDCYP17A1S1PR1CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093026-A | Liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-03-03 | — | — | US | disclosed |
| WO-1990008756-A1 | DIPHENYLETHANES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-09 | — | — | WO | disclosed |