Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1978763 | 0.84 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL15923143 | 0.78 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL28300098 | 0.77 | — | — | |
| SCHEMBL1978579 | 0.76 | — | — | |
| SCHEMBL797512 | 0.76 | SPHK1 (0.38) | — | |
| SCHEMBL152342 | 0.75 | SPHK1 (0.41) | TBXAS1 | |
| SCHEMBL5898950 | 0.75 | SPHK1 (0.41) | TBXAS1 | |
| SCHEMBL1011862 | 0.75 | SPHK1 (0.41) | TBXAS1 | |
| SCHEMBL155171 | 0.74 | SPHK1 (0.33) | — | |
| SCHEMBL145955 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811462-A | (BICYCLO(2.2.1)HEPT-5'-EN-2'-YL-CARBONYL)AMINO-3-HYDROXY DERIVATIVES | MERCK & CO., INC. (US) | 1998-09-22 | — | — | US | disclosed |