Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605444 | 0.78 | HRH3 (0.56) | HRH3CYP2C9TSHRITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8838061 | 0.77 | HRH3 (0.53) | HRH3CYP2C9MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9024564 | 0.76 | SMN1; SMN2 (0.50) | HRH3ITGB3ITGA2B | |
| SCHEMBL8699538 | 0.76 | ITGB3 (0.53) | HRH3CYP2C9TSHRITGB3ITGA2B | |
| SCHEMBL6603738 | 0.75 | CYP2C9 (0.73) | CYP2C9TSHRMEN1KMT2A | |
| SCHEMBL7401896 | 0.74 | HRH3 (0.62) | HRH3CYP2C9TSHRITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6207497 | 0.73 | HRH3 (0.61) | HRH3CYP2C9TSHRITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL9058256 | 0.72 | ITGB3 (0.60) | HRH3ITGB3ITGA2BKMT2A | |
| Hydrochloric Acid SCHEMBL9023569 | 0.72 | HTR7 (0.48) | HRH3CYP2C9TSHRITGB3ITGA2B | |
| SCHEMBL8837987 | 0.72 | ITGB3 (0.63) | HRH3ITGB3ITGA2BDRD4SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |