SCHEMBL8632756

SCHEMBL8632756

CCOc1ccc(Oc2ccc(OCC=C(Br)Br)cc2C(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.39
LTA4H P09960 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 1/20 0.38
ATM Q13315 1/20 0.38
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
KDM4E B2RXH2 1/20 0.36
NQO1 P15559 1/20 0.36
CACNA1C Q13936 1/20 0.36
THRB P10828 1/20 0.35
RORC P51449 1/20 0.35
P2RX3 P56373 1/20 0.35
P2RX2 Q9UBL9 1/20 0.35
GAA P10253 1/20 0.35
AKR1C3 P42330 1/20 0.34
AKR1C2 P52895 1/20 0.34
ACACB O00763 1/20 0.34
ACACA Q13085 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634769 0.90 LTA4H (0.42) MAPTLTA4HL3MBTL1LMNAATM
SCHEMBL8633420 0.87 MAPT (0.42) MAPTLTA4HL3MBTL1LMNAATM
SCHEMBL8635872 0.84 THRB (0.41) MAPTSLC6A4THRBRORCACACB
SCHEMBL8633956 0.84 MAPT (0.41) MAPTLTA4HL3MBTL1LMNAATM
SCHEMBL8632315 0.82 KDM4E (0.38) L3MBTL1KDM4ETHRBRORCP2RX3
SCHEMBL8635107 0.81 SLC6A2 (0.36) MAPTLTA4HL3MBTL1LMNAATM
SCHEMBL8636446 0.80 LTA4H (0.40) MAPTLTA4HL3MBTL1LMNAATM
SCHEMBL8635020 0.80 LTA4H (0.40) LTA4HL3MBTL1KDM4ETHRBRORC
SCHEMBL8637643 0.80 THRB (0.40) MAPTTHRBRORCP2RX3P2RX2
SCHEMBL8632604 0.79 ACACB (0.37) THRBRORCP2RX3P2RX2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed