Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.42 |
| ▸ | KDM4A | O75164 | 5/20 | 0.35 |
| ▸ | KDM5C | P41229 | 5/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.35 |
| ▸ | KDM4B | O94953 | 4/20 | 0.35 |
| ▸ | KDM6B | O15054 | 2/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.35 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9929411 | 0.75 | DAO (0.60) | DAOKDM4AKDM5CKDM5BKDM6B | |
| SCHEMBL17626098 | 0.72 | KMO (0.51) | KDM4AKDM5CKDM5BKDM4BKDM6B | |
| SCHEMBL937917 | 0.69 | DAO (0.41) | DAOKDM4AKDM5CKDM5BKDM4B | |
| SCHEMBL938585 | 0.69 | DAO (0.41) | DAOKDM4AKDM5CKDM5BKDM4B | |
| SCHEMBL940633 | 0.68 | DAO (0.47) | DAOKDM4AKDM5CKDM5BKDM4B | |
| SCHEMBL939441 | 0.68 | JMJD6 (0.54) | DAOKDM4AKDM5CKDM5BKDM4B | |
| SCHEMBL939466 | 0.67 | NAPRT (0.52) | DAOKDM4AKDM5CKDM5BKDM6B | |
| SCHEMBL13992625 | 0.66 | KDM5C (0.49) | DAOKDM4AKDM5CKDM5BKDM4B | |
| SCHEMBL938500 | 0.66 | KMO (0.52) | DAOKDM4EALDH1A1POLBGAA | |
| SCHEMBL939164 | 0.62 | GPR35 (0.45) | DAOIKBKETBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |