SCHEMBL8633131

SCHEMBL8633131

Cc1ccccc1Nc1nc(S)nc(S)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.51
NPC1 O15118 4/20 0.51
RAB9A P51151 4/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
LMNA P02545 2/20 0.51
PKM P14618 1/20 0.51
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
NPSR1 Q6W5P4 3/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
NTSR1 P30989 1/20 0.50
CYP2C19 P33261 1/20 0.50
KMT2A Q03164 1/20 0.50
SLC2A1 P11166 2/20 0.49
LRRK2 Q5S007 1/20 0.46
CCNA2 P20248 1/20 0.45
CDK2 P24941 1/20 0.45
CDK5 Q00535 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13750837 0.86 HTT (0.59) HTTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL8629458 0.78 KMT2A (0.51) HTTNPC1RAB9ASMN1; SMN2PKM
SCHEMBL23630435 0.77 TSHR (0.67) NPC1RAB9ASMN1; SMN2NPSR1KMT2A
SCHEMBL30202205 0.77 TSHR (0.67) NPC1RAB9ASMN1; SMN2NPSR1KMT2A
SCHEMBL10939229 0.77 TSHR (0.67) HTTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL23795778 0.77 NPC1 (0.71) HTTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL4544852 0.77 SLC2A1 (0.65) HTTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL9483332 0.77 NPSR1 (0.54) HTTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL4544839 0.77 SLC2A1 (0.65) HTTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL16628856 0.77 MEN1 (0.46) RAB9ALMNANFKB1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110894358-B Organic-inorganic hybrid composition, article and optical component comprising the same 三星电子株式会社 2023-07-28 CN disclosed
US-11312840-B2 Organic-inorganic hybrid composition, and article and optical component including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-04-26 US disclosed
US-20200062927-A1 ORGANIC-INORGANIC HYBRID COMPOSITION, AND ARTICLE AND OPTICAL COMPONENT INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-02-27 US disclosed
EP-0508390-B1 Light-sensitive silver halide photographic material KONISHIROKU PHOTO IND (JP) 1998-07-01 EP disclosed
US-5569545-A LAMINATE HAVING COPPER FOIL WITH METAL ALLOY LAYER ON SIDE TO BE BONDED WITH INSULATING LAYER, SAID LAYERS BEING CROSSLINKED WITH EACH OTHER BY SULFUR BONDS NIPPON DENKAI LTD. (JP) 1996-10-29 US disclosed
US-5258280-A 2-amino-4,6-dimercapto-1,3,5-triazine derivatives; blackness, high covering power KONICA CORPORATION (JP) 1993-11-02 US disclosed
EP-0508390-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1992-10-14 EP disclosed