Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633131 | 0.78 | HTT (0.51) | KMT2ANPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL29196035 | 0.76 | RAPGEF4 (0.71) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11615704 | 0.73 | RAB9A (0.49) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11564238 | 0.71 | RAPGEF4 (0.61) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1921826 | 0.70 | RAPGEF4 (0.63) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17858219 | 0.69 | RAPGEF4 (0.61) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1921827 | 0.69 | RAPGEF4 (0.61) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17858100 | 0.69 | RAPGEF4 (0.61) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14438164 | 0.68 | KCNH3 (0.55) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL655868 | 0.68 | AURKA (0.58) | SRCSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508390-B1 | Light-sensitive silver halide photographic material | KONISHIROKU PHOTO IND (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5258280-A | 2-amino-4,6-dimercapto-1,3,5-triazine derivatives; blackness, high covering power | KONICA CORPORATION (JP) | 1993-11-02 | — | — | US | disclosed |
| EP-0508390-A2 | Light-sensitive silver halide photographic material | KONICA CORPORATION (JP) | 1992-10-14 | — | — | EP | disclosed |