Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967288 | 0.82 | EDNRA (0.49) | CA2CA1EDNRACA9ALOX5AP | |
| SCHEMBL1667127 | 0.82 | EDNRA (0.49) | CA2CA1EDNRACA9ALOX5AP | |
| SCHEMBL7778063 | 0.81 | CA2 (0.51) | CA2CA1CA9CA12 | |
| SCHEMBL8632289 | 0.80 | AKR1B1 (0.40) | CA2CA1CA9CA12 | |
| SCHEMBL8630958 | 0.80 | LRRK2 (0.48) | CA2CA1IDO1 | |
| SCHEMBL8697589 | 0.79 | ALOX5AP (0.47) | CA2CA1EDNRACA9ALOX5AP | |
| SCHEMBL8627632 | 0.78 | CA1 (0.42) | CA2CA1CA9CA12 | |
| SCHEMBL8634777 | 0.78 | CA1 (0.40) | CA2CA1CA9CA12 | |
| SCHEMBL8629397 | 0.78 | ALOX5AP (0.40) | CA2CA1CA9ALOX5APFEN1 | |
| SCHEMBL3463943 | 0.77 | KDM4E (0.48) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |