Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 6/20 | 0.40 |
| ▸ | FEN1 | P39748 | 6/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631181 | 0.83 | PTGS2 (0.50) | ALOX5APFEN1CA9 | |
| SCHEMBL8627632 | 0.83 | CA1 (0.42) | CA1CA2CA4CA6CA12 | |
| SCHEMBL8634777 | 0.83 | CA1 (0.40) | PTGES2CA1CA2CA4CA6 | |
| SCHEMBL8632289 | 0.82 | AKR1B1 (0.40) | CA1CA2CA4CA6CA12 | |
| SCHEMBL7779263 | 0.82 | PTGS2 (0.51) | SCDCA1CA2CA12CA9 | |
| SCHEMBL8631499 | 0.81 | FABP1 (0.41) | ALOX5APFEN1PTGES2CA1CA2 | |
| SCHEMBL8629486 | 0.80 | ALOX5AP (0.44) | ALOX5APFEN1PTGES2CA2CA12 | |
| SCHEMBL8632812 | 0.80 | ALOX5AP (0.47) | ALOX5APFEN1 | |
| SCHEMBL8631047 | 0.80 | ALOX5AP (0.42) | ALOX5APFEN1PTGES2 | |
| SCHEMBL2568298 | 0.79 | ALOX5AP (0.49) | ALOX5APFEN1PTGES2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |