Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631058 | 0.92 | PTGS2 (0.50) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL8629220 | 0.90 | PTGS2 (0.51) | PTGS2PTGS1KIF11CYP2C9 | |
| SCHEMBL8634941 | 0.89 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL8631183 | 0.88 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL8633265 | 0.88 | PTGS2 (0.58) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL8630947 | 0.88 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL8632515 | 0.86 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL8632596 | 0.85 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL8630523 | 0.84 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL8632648 | 0.84 | PTGS2 (0.54) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |