Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316954 | 0.83 | GAA (0.48) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL53468 | 0.82 | GAA (0.47) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL10944770 | 0.82 | TSHR (0.51) | GAAMAPTTP53GLAALDH1A1 | |
| SCHEMBL29510603 | 0.82 | GAA (0.47) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL6812884 | 0.82 | GAA (0.47) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL10949384 | 0.81 | GAA (0.52) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL10950577 | 0.80 | ALDH1A1 (0.52) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL7801293 | 0.80 | PTK2 (0.48) | GAAMAPTTP53GLAALDH1A1 | |
| SCHEMBL8780754 | 0.80 | GAA (0.45) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL8780753 | 0.80 | GAA (0.45) | GAAMAPTTP53GLACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847140-A | Intermediates for the manufacture of herbicidal 1-{ 2-(cyclopropylcarbonyl) Phenyl! Sulfamoyl}-3-(4,6-dialkoxy-2-pyrimidinyl) urea compounds | AMERICAN CYANAMID COMPANY (US) | 1998-12-08 | — | — | US | disclosed |