Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633788 | 0.75 | — | — | |
| Bromide SCHEMBL2446627 | 0.70 | HIF1A (0.55) | SNCAHIF1A | |
| Bromide SCHEMBL8630306 | 0.69 | LMNA (0.39) | — | |
| Bromide SCHEMBL5783552 | 0.67 | ABCG2 (0.41) | SNCAHIF1A | |
| Hydrochloric Acid SCHEMBL9292231 | 0.66 | HIF1A (0.55) | SNCAHIF1A | |
| Bromide SCHEMBL5598389 | 0.66 | HIF1A (0.44) | SNCAHIF1A | |
| SCHEMBL16043398 | 0.66 | HTR2C (0.33) | — | |
| Bromide SCHEMBL1354269 | 0.66 | HIF1A (0.44) | SNCAHIF1A | |
| Bromide SCHEMBL8464686 | 0.65 | HIF1A (0.48) | SNCAHIF1A | |
| SCHEMBL9461073 | 0.65 | HIF1A (0.48) | SNCAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712281-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |