SCHEMBL8633502

SCHEMBL8633502

C=C(COCC(=O)OC)C(N)=O

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.37
HSD17B10 Q99714 1/20 0.34
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3980516 0.84 TDP1 (0.38) TDP1LMNAALDH1A1
SCHEMBL1335833 0.79 TSHR (0.56) TSHRHSD17B10MGAMGAASI
Ether SCHEMBL8665518 0.78 ALOX15 (0.37) TSHRTDP1ALDH1A1
SCHEMBL5840370 0.78 TSHR (0.43) TSHRHSD17B10MGAMGAASI
SCHEMBL27160218 0.78 MGAM (0.46) TSHRHSD17B10MGAMGAASI
SCHEMBL24978678 0.77 TDP1 (0.35) TDP1
SCHEMBL1011995 0.76
SCHEMBL7889399 0.76 MGAM (0.44) TSHRHSD17B10MGAMGAASI
SCHEMBL1000321 0.75
SCHEMBL8893700 0.75 TSHR (0.46) TSHRHSD17B10MGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0539729-B1 Development inhibitor reflector layers EASTMAN KODAK CO (US) 1998-07-15 EP disclosed
US-5512414-A ELEMENT CONTAINING MORDANT LAYER FOR BINDING DIFFUSIBLE DYES, LAYER CONTAINING SOLID PARTICLE DISPERSION OF DIFFUSIBLE DYE FORMING COMPOUND, BARRIER LAYER WHICH BLOCKS DIFFUSION OF DYE OUT OF ELEMENT EASTMAN KODAK COMPANY (US) 1996-04-30 US disclosed
US-5441854-A Photographic image forming process utilizing a barrier layer for diffusible dye containment EASTMAN KODAK COMPANY (US) 1995-08-15 US disclosed
US-5370967-A Polymeric barrier to control diffusion EASTMAN KODAK COMPANY (US) 1994-12-06 US disclosed
US-5342730-A With mordant and stripping layers EASTMAN KODAK COMPANY (US) 1994-08-30 US disclosed
US-5322758-A Integral color diffusion transfer element for large volume development EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
EP-0590567-A1 Integral color diffusion transfer element for large volume development EASTMAN KODAK COMPANY (US) 1994-04-06 EP disclosed
EP-0590566-A1 Barrier layer for dye containment in photographic elements EASTMAN KODAK COMPANY (US) 1994-04-06 EP disclosed
EP-0590565-A1 Image separation system for large volume development EASTMAN KODAK COMPANY (US) 1994-04-06 EP disclosed
US-5288745-A Diffusion transfer for color photography; polymeric mordant dye barrier layers EASTMAN KODAK COMPANY (US) 1994-02-22 US disclosed
US-5254441-A Barrier polymer layer of hydrophobic and ionic hydrophilic unsaturated monomers EASTMAN KODAK COMPANY (US) 1993-10-19 US disclosed
EP-0539729-A1 Development inhibitor reflector layers EASTMAN KODAK COMPANY (US) 1993-05-05 EP disclosed