Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 1/20 | 0.40 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.40 |
| ▸ | HPD | P32754 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634935 | 0.84 | ALDH1A1 (0.37) | KCNJ6KCNJ3KDM4EL3MBTL1MEN1 | |
| SCHEMBL12336755 | 0.77 | KDM4E (0.54) | HPDKDM4EPOLBMAPTTHRB | |
| SCHEMBL8628790 | 0.73 | ALDH1A1 (0.41) | KDM4EPOLBMAPTTHRBRECQL | |
| SCHEMBL23203438 | 0.69 | KCNJ6 (0.49) | KCNJ6KCNJ3KDM4EMAPTTRPV4 | |
| SCHEMBL30783211 | 0.69 | KCNJ6 (0.49) | KCNJ6KCNJ3KDM4EMAPTTRPV4 | |
| SCHEMBL8848783 | 0.67 | KDM4E (0.49) | KDM4ENR1I2CACNA1BALDH1A1GAA | |
| SCHEMBL9779877 | 0.67 | KMT2A (0.50) | HPDKDM4EPOLBMAPTTHRB | |
| SCHEMBL12345802 | 0.66 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL2061070 | 0.66 | ALDH1A1 (0.47) | KCNJ6KCNJ3KDM4EPOLBMAPT | |
| SCHEMBL2062193 | 0.66 | HSD11B1 (0.56) | KCNJ6KCNJ3MAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003045-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-30 | — | — | WO | claimed |
| EP-0850218-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997003045-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-30 | — | — | WO | disclosed |