Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630069 | 0.95 | MEN1 (0.48) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL8634602 | 0.83 | TDP1 (0.56) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL8633552 | 0.83 | TDP1 (0.63) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL8630900 | 0.83 | TDP1 (0.52) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL8633719 | 0.78 | MEN1 (0.53) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL8634208 | 0.77 | MEN1 (0.58) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL8630774 | 0.77 | MEN1 (0.49) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL8633442 | 0.77 | TDP1 (0.42) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL8630894 | 0.76 | TDP1 (0.61) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL8633773 | 0.76 | MEN1 (0.57) | TDP1MEN1KMT2AGAAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | claimed |