Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633833 | 0.96 | SYK (0.40) | TDP1NPSR1SYKMEN1GAA | |
| SCHEMBL8633439 | 0.82 | NPSR1 (0.46) | TDP1NPSR1SYKDRD2MAPT | |
| SCHEMBL8883484 | 0.79 | PTPRB (0.45) | TDP1NPSR1SYKDRD2MAPT | |
| SCHEMBL8632625 | 0.77 | IDO1 (0.46) | TDP1NPSR1SYKGAAL3MBTL1 | |
| SCHEMBL8633540 | 0.77 | IDO1 (0.46) | TDP1NPSR1SYKMEN1GAA | |
| SCHEMBL8633561 | 0.77 | TDP1 (0.48) | TDP1NPSR1MEN1GAAKMT2A | |
| SCHEMBL8630758 | 0.73 | IDO1 (0.44) | TDP1NPSR1SYKMEN1GAA | |
| SCHEMBL8630069 | 0.72 | MEN1 (0.48) | TDP1MEN1GAAKMT2ADRD2 | |
| SCHEMBL20590258 | 0.72 | TDP1 (0.58) | TDP1NPSR1MEN1GAAKMT2A | |
| SCHEMBL14985078 | 0.71 | IDO1 (0.52) | TDP1NPSR1MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | claimed |