Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633571 | 0.84 | MEN1 (0.41) | ALDH1A1MEN1KMT2ASLC6A3 | |
| SCHEMBL11109111 | 0.82 | MEN1 (0.44) | ALDH1A1RECQLMMP8KDM4EPIN1 | |
| Lithium Ion SCHEMBL8633570 | 0.81 | MEN1 (0.39) | ALDH1A1MEN1KMT2ASLC6A3 | |
| SCHEMBL8634342 | 0.81 | CYSLTR2 (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8634364 | 0.77 | PTPN1 (0.35) | ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7431853 | 0.76 | ALDH1A1 (0.57) | ALDH1A1RECQLMMP8PIN1MEN1 | |
| SCHEMBL9115989 | 0.75 | MEN1 (0.40) | ALDH1A1RECQLMMP8KDM4EPIN1 | |
| SCHEMBL8762918 | 0.74 | MEN1 (0.46) | ALDH1A1PIN1MEN1KMT2ASLC6A3 | |
| SCHEMBL3609772 | 0.74 | CYP4F2 (0.41) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9208553 | 0.73 | ALDH1A1 (0.37) | ALDH1A1PIN1MEN1KMT2ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| EP-0667850-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS. | DOMPE FARMACEUTICI SPA (IT) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |