Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 11/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633126 | 0.86 | ALOX5 (0.44) | CYSLTR2CYSLTR1HTTALOX5HDAC6 | |
| SCHEMBL8633596 | 0.81 | ALDH1A1 (0.44) | MEN1ALDH1A1KMT2A | |
| SCHEMBL8632623 | 0.73 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1ALOX5CYP1A2MEN1 | |
| SCHEMBL27487179 | 0.69 | ALDH1A1 (0.62) | CYSLTR2CYSLTR1HTTCYP1A2MEN1 | |
| SCHEMBL3609772 | 0.68 | CYP4F2 (0.41) | CYP1A2MEN1ALDH1A1KMT2A | |
| SCHEMBL8827894 | 0.67 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1ALOX5HDAC6CYP1A2 | |
| SCHEMBL11109111 | 0.67 | MEN1 (0.44) | KDM4CMEN1ALDH1A1KMT2A | |
| SCHEMBL8634364 | 0.67 | PTPN1 (0.35) | CYP1A2ALDH1A1 | |
| SCHEMBL8762918 | 0.66 | MEN1 (0.46) | KDM4CMEN1ALDH1A1KMT2A | |
| SCHEMBL8762920 | 0.66 | ALDH1A1 (0.41) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| EP-0667850-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS. | DOMPE FARMACEUTICI SPA (IT) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |