Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633590 | 1.00 | TSHR (0.46) | TSHRL3MBTL1TDP1ALDH1A1HSD17B10 | |
| SCHEMBL26670106 | 0.86 | TSHR (0.56) | TSHRL3MBTL1TDP1ALDH1A1HSD17B10 | |
| SCHEMBL11860940 | 0.86 | TSHR (0.56) | TSHRL3MBTL1TDP1ALDH1A1HSD17B10 | |
| SCHEMBL319886 | 0.85 | ALDH1A1 (0.51) | TSHRALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL319889 | 0.85 | ALDH1A1 (0.51) | TSHRALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL13703243 | 0.82 | TSHR (0.49) | TSHRL3MBTL1TDP1ALDH1A1HSD17B10 | |
| SCHEMBL28294255 | 0.82 | TSHR (0.51) | TSHRL3MBTL1TDP1ALDH1A1HSD17B10 | |
| SCHEMBL4544966 | 0.82 | TSHR (0.51) | TSHRL3MBTL1TDP1ALDH1A1HSD17B10 | |
| SCHEMBL9815576 | 0.80 | TSHR (0.53) | TSHRL3MBTL1TDP1ALDH1A1HSD17B10 | |
| SCHEMBL9095382 | 0.77 | CES2 (0.56) | TSHRL3MBTL1TDP1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10055067-A | — | — | None | — | — | JP | disclosed |
| JP-H1055067-A | PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL AND IMAGE FORMING METHOD | KONICA CORP | 1998-02-24 | — | — | JP | disclosed |