Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3294154 | 0.85 | NOS1 (0.42) | MEN1KMT2ALTA4HNOS1CYP2C9 | |
| SCHEMBL2886165 | 0.80 | CYP2C9 (0.40) | POLBNOS1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL17449764 | 0.80 | NOS1 (0.40) | TDP1MEN1KMT2ALTA4HNOS1 | |
| SCHEMBL5763676 | 0.80 | NOS1 (0.40) | TDP1MEN1KMT2ALTA4HNOS1 | |
| SCHEMBL67350 | 0.80 | NOS1 (0.40) | TDP1MEN1KMT2ALTA4HNOS1 | |
| SCHEMBL25412373 | 0.80 | NOS1 (0.43) | MEN1KMT2ALTA4HNOS1CYP2C9 | |
| SCHEMBL67349 | 0.80 | NOS1 (0.40) | TDP1MEN1KMT2ALTA4HNOS1 | |
| SCHEMBL20671217 | 0.79 | CYP1A2 (0.43) | POLBKMT2ALTA4HNOS1CYP2C9 | |
| SCHEMBL2254267 | 0.79 | CYP1A2 (0.43) | POLBKMT2ALTA4HNOS1CYP2C9 | |
| SCHEMBL31229277 | 0.79 | CYP1A2 (0.43) | POLBKMT2ALTA4HNOS1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254080-B1 | MALONIC ACID DERIVATIVES AND METHODS FOR THEIR SYNTHESIS | ENIRICERCHE S.p.A. (IT) | 1993-03-17 | — | — | EP | claimed |
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| EP-0667850-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS. | DOMPE FARMACEUTICI SPA (IT) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |