Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439253 | 0.99 | MAPT (0.41) | MAPTKMT2AHPGDCYP2C9ALDH1A1 | |
| SCHEMBL8672637 | 0.93 | SMN1; SMN2 (0.37) | MAPTKMT2AHPGDCYP2C9ALDH1A1 | |
| SCHEMBL8670481 | 0.91 | ALDH1A1 (0.36) | MAPTKMT2AHPGDCYP2C9ALDH1A1 | |
| SCHEMBL8668983 | 0.87 | MEN1 (0.36) | MAPTKMT2AHPGDALDH1A1LMNA | |
| SCHEMBL7923747 | 0.85 | KDM4E (0.41) | MAPTKMT2AHPGDALDH1A1LMNA | |
| SCHEMBL8553022 | 0.84 | KDM4E (0.40) | MAPTKMT2AHPGDALDH1A1LMNA | |
| SCHEMBL1559770 | 0.83 | MAPT (0.50) | MAPTKMT2AHPGDCYP2C9ALDH1A1 | |
| SCHEMBL1559910 | 0.83 | MAPT (0.50) | MAPTKMT2AHPGDCYP2C9ALDH1A1 | |
| SCHEMBL8553044 | 0.81 | MAPT (0.32) | MAPTALDH1A1LMNANPC1SMN1; SMN2 | |
| SCHEMBL8442774 | 0.81 | HTR1D (0.44) | KMT2ALMNAGAAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840917-A | ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5239079-A | Pyridinium salt and pharmacological composition containing the same | EISAI CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| US-5162317-A | PYRIDINIUM SALT AND PHARMACOLOGICAL COMPOSITION CONTAINING THE SAME | ESAI CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0374261-A1 | PYRIDINIUM SALT AND PHARMACOLOGICAL COMPOSITION CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |
| WO-1989010927-A1 | PYRIDINIUM SALT AND PHARMACOLOGICAL COMPOSITION CONTAINING THE SAME | EISAI CO., LTD. (JP) | 1989-11-16 | — | — | WO | disclosed |