Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NCF1 | P14598 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7923747 | 0.99 | KDM4E (0.41) | KDM4ENCF1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL8668983 | 0.86 | MEN1 (0.36) | KDM4EHSD17B10SMN1; SMN2LMNARAB9A | |
| SCHEMBL8553044 | 0.86 | MAPT (0.32) | SMN1; SMN2LMNATSHRMAPTALDH1A1 | |
| SCHEMBL8672637 | 0.86 | SMN1; SMN2 (0.37) | KDM4EHSD17B10SMN1; SMN2LMNARAB9A | |
| SCHEMBL8550788 | 0.85 | RPS6KA5 (0.37) | KDM4ENCF1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL8439253 | 0.85 | MAPT (0.41) | KDM4EHSD17B10SMN1; SMN2LMNARAB9A | |
| SCHEMBL8550417 | 0.85 | RXRA (0.34) | NCF1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8633727 | 0.84 | MAPT (0.41) | KDM4EHSD17B10SMN1; SMN2LMNARAB9A | |
| SCHEMBL8670481 | 0.84 | ALDH1A1 (0.36) | KDM4EHSD17B10SMN1; SMN2LMNARAB9A | |
| SCHEMBL1559770 | 0.82 | MAPT (0.50) | KDM4EHSD17B10LMNARAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |