Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | CTSG | P08311 | 3/20 | 0.39 |
| ▸ | CMA1 | P23946 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747874 | 0.85 | LMNA (0.63) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7747815 | 0.85 | LMNA (0.63) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7747396 | 0.83 | CTSK (0.48) | MAPT | |
| SCHEMBL7748905 | 0.82 | CTSK (0.49) | MAPT | |
| SCHEMBL7747407 | 0.82 | CTSK (0.49) | MAPT | |
| SCHEMBL7748967 | 0.79 | LMNA (0.55) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8635675 | 0.79 | LMNA (0.55) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7743253 | 0.79 | LMNA (0.55) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8635229 | 0.79 | LMNA (0.55) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7743265 | 0.79 | LMNA (0.55) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767282-A | Method for the preparation of taxol and its derivatives | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-06-16 | — | — | US | disclosed |